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RNA-triggered cell killing with CRISPR–Cas12a2

Paul Scholz

Nature, Published online: 06 May 2026; doi:10.1038/s41586-026-10466-y

Cas12a2 enables RNA-triggered, sequence-specific killing of eukaryotic cells via widespread DNA shredding, allowing selective elimination of cells on the basis of gene expression, including virus-infected or mutation-bearing cells. Read More Nature

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